Xenotransplantation of human thyroid carcinomas in athymic nude mice

H. J. C. Wenisch

doi:10.1055/s-0029-1211690

RSS-Feed abonnieren

Bitte kopieren Sie die angezeigte URL und fügen sie dann in Ihren RSS-Reader ein.

https://www.thieme-connect.de/rss/thieme/de/10.1055-s-00000017.xml

Teilen / Bookmarken

Facebook Linkedin Weibo

PDF herunterladen

Exp Clin Endocrinol Diabetes 1996; 104: 61-63
DOI: 10.1055/s-0029-1211690

Goiter - malignant disease

Xenotransplantation of human thyroid carcinomas in athymic nude mice

H. J. C. Wenisch

Dept. of Surgery, Div. of General Surgery (Head: Prof. Dr. A. Encke), Johann Wolfgang Goethe-University, Frankfurt am Main, Germany

Weitere Informationen

Publikationsverlauf

Publikationsdatum:
15. Juli 2009 (online)

Auch verfügbar auf

als PDF herunterladen Lizenzen und Reprints

Summary

A nude mouse xenotransplantation model was established for human thyroid carcinomas of different histological types. Best results of serial passages were obtained in anaplastic cancers. The models allowed investigations under in vivo conditions. Hormonal influences were tested, and imaging procedures were possible. In most aggressive anaplastic carcinoma cell lines, growth inhibition of cytostatic drugs, cytokines and nutritional effects were investigated.

Key words

Xenotransplantation - thyroid carcinoma